Coagulation Profile Study in Pregnancy Induced Hypertension

AIM OF THE STUDY: To study coagulation profile changes in pregnancy induced hypertension. OBJECTIVES: 1. To study the changes in platelet count, bleeding time, clotting time, prothrombin time and activated partial thromboplastin time in pregnancy induced hypertension. 2. To study the above parameters in normal pregnant women. 3. To compare the above parameters between normotensive pregnant women and women with pregnancy induced hypertension. 4. To correlate the above parameters with severity of pregnancy induced hypertension. METHODS AND MATERIALS: Control group consists of 60 normotensive pregnant women compared with 30 cases of non-severe PIH and 30 cases of severe PIH. Coagulation parameters BT, CT, Platelet Count, PT and APTT were done for all cases. OBSERVATIONS: Patients with severe PIH patients showed low Platelet Count, prolonged BT, PT and APTT compared to normotensive pregnant women and non-severe PIH. No changes observed in CT. SUMMARY AND CONCLUSION: The changes in Coagulation Profile in severe PIH is helpful in assessing the Coagulation abnormalities at earlier stage. Changes observed in the coagulation parameters as the severity of PIH increases.