Diagnostic performance of computed tomographic coronary angiography for evaluation of coronary artery stensosis in individuals with typical or atypical chest pain without known Coronary Artery Disease

AIM & OBJECTIVE: Primary Aim of the study: 1. Detection of coronary artery stenosis with CT coronary angiography in comparison with conventional coronary angiography. 2. Correlation of grading of stenosis in CT coronary angiography with conventional coronary angiography Secondary aim To assess the normal luminal diameter of coronary arteries on CT coronary angiography in Indian population MATERIAL AND METHODS: In our prospective cohort study, which includes 20 patients presenting with typical/ atypical chest pain who underwent both CT and catheter coronary angiogram were included in the study. Vessels were analyzed on segment basis for any stenosis if so they were graded accordingly. RESULTS: Stenosis of more than 50% was considered as significant stenosis. Sensitivity, specificity, PPV and NPV for significant stenosis were 93%, 98%. 90% and 98% respectively in our study. Over all sensitivity, specificity, PPV and NPV for detecting stenosis in CT was. 87.8%, 97.9%, 92.3 %and 96.5% respectively. CONCLUSION: Based on the study CT coronary angiography is sensitive in detecting clinically significant stenosis provided the quality of the image is adequate.