Assessment of Coronary Artery Stenosis with 16 Slices Multidetector CT

Objective: To investigate the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of noninvasive coronary computer tomography (CT) for assessment of coronary arteries. Methods: The total of 330 patients who were suspected to have coronary artery disease underwent noninvasive coronary CT angiography. The 26 patients (male 14: female 12) had consecutively undergone a 16 slices multi-detector row CT, as well as invasive coronary angiography, within a 3 months period. The coronary CT angiography was retrospectively reviewed by two radiologists. The degree of coronary stenosis was compared with invasive conventional angiography. Results: The coronary CT angiography of 306 segments in 26 patients was evaluated. The 306 segments were divided into proximal 155 branches and distal 151 branches. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of coronary CT angiography for coronary artery stenosis were 76.9%, 91.7%, 65.6%, 95.1%, and 89.2% respectively. The sensitivity and specificity of proximal coronary artery stenosis 155 segments were 85.7%, and 90.8%, respectively. The sensitivity and specificity for 151 distal branches were 58.8% and 92.5%, respectively. Conclusion: Coronary CT angiography using 16 slices multi-detector row CT allows for the reliable detection of coronary artery stenoses with a high diagnostic accuracy.