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[Optimal extraction of Dingxiang jiangqi granules].

Lihong Zhang, Yan Fu, Zhirong Zhang, Jianxin Wang, MA Shu-ying, Zhu Sheng-liang

Abstract

OBJECTIVE: To screen and optimize the extraction of Dingxiangjiangqi granules. METHOD: The extraction route was screened by using pharmacodynamic experiment and the extraction conditions were optimized by orthogonal design and taking extract yield, content of naringin and tetrahydropalmatine as indexes. RESULT: The pharmacodynamic result showed that aqueous extract had the best effect to cure the esophagitis of rats and the optimized extraction technique was adding 12 times water, extracting 0. 5 hour for 3 times. CONCLUSION: The optimum extraction was simple, reasonable, stable and useful for further development.

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Available abstract

Key concepts: Extraction (chemistry), Naringin, Tetrahydropalmatine, Chromatography, Yield (engineering), Pharmacodynamics, Chemistry, Materials science