[Antibacterial spectrum of antibacterial peptides from Musca domestica larvae and synergic interaction between the peptides and antibiotics].
Xia Gong, Guo-Wei Le, Yunfei Li
Abstract
Xia Gong, Guo-Wei Le, Yunfei Li
Abstract
In vitro antibacterial activities of three antibacterial peptides, alone and in combination with the antibiotics were measured by MIC and antibacterial spectrum. Synergy was observed when the peptides were combined with penicillin, streptomycin by FIC. The results show that antibacterial peptides have stronger inhibition of pathogenic bacterium, and antibacterial spectrum are very different. The interaction in antibacterial peptides, antibiotics and bacterium is extraordinary complex, except synergic action, there are antagonism and indifference.
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In vitro antibacterial activities of three antibacterial peptides, alone and in combination with the antibiotics were measured by MIC and antibacterial spectrum. Synergy was observed when the peptides were combined with penicillin, streptomycin by FIC. The results show that antibacterial peptides have stronger inhibition of pathogenic bacterium, and antibacterial spectrum are very different. The interaction in antibacterial peptides, antibiotics and bacterium is extraordinary complex, except synergic action, there are antagonism and indifference.
Key concepts: Antibacterial peptide, Antibacterial activity, Antibiotics, Streptomycin, Penicillin, Microbiology, Chemistry, Antagonism