2012•Natural Product CommunicationsOpen access

Inhibitory Effect of Hexahydrocurcumin on Human Platelet Aggregation

Huei‐Ping Dong, Rei‐Cheng Yang, I‐Chun Chunag, Li‐Ju Huang, Hsing-Tan Li, Hsin‐Liang Chen, Chung‐Yi Chen

Abstract

The effects of hexahydrocurcumin on adenosine diphosphate (ADP)-induced human platelet aggregation were studied. Treatment of human platelet-rich plasma with hexahydrocurcumin resulted in an inhibitory effect on platelet aggregation, suggesting the potential of this compound as an anti-atherosclerogenic agent in humans.

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Key concepts: Platelet, Adenosine diphosphate, Platelet aggregation, Inhibitory postsynaptic potential, Human plasma, Chemistry, Platelet-rich plasma, Adenosine