Effects of Morroniside on Platelet Aggregation in Rabbit
Wei Wang
Abstract
Wei Wang
Abstract
Objective To study the effects of Morroniside on platelet aggregation in rabbits induced by Adenosine diphosphate(ADP),Arachidonic acid(AA),Platelet activating factor(PAF).MethodsThe platelet aggregation was determined by Born's method.ResultsCompared with the controls,Morroniside inhibited platelet aggregation induced by ADP,AA,PAF(P0.001)and especially selective on ADP.ConclusionMorroniside inhibited platelet aggregation in rabbits,especially induced by ADP.
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Objective To study the effects of Morroniside on platelet aggregation in rabbits induced by Adenosine diphosphate(ADP),Arachidonic acid(AA),Platelet activating factor(PAF).MethodsThe platelet aggregation was determined by Born's method.ResultsCompared with the controls,Morroniside inhibited platelet aggregation induced by ADP,AA,PAF(P0.001)and especially selective on ADP.ConclusionMorroniside inhibited platelet aggregation in rabbits,especially induced by ADP.
Key concepts: Adenosine diphosphate, Arachidonic acid, Platelet, Platelet aggregation, Platelet-activating factor, Chemistry, Adenosine, Pharmacology