2016European Journal of Medicinal ChemistryOpen access

Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues

Mariagrazia Roselli, Alessia Carocci, Roberta Budriesi, Matteo Micucci, Maddalena Toma, Lorenzo Di Cesare Mannelli, Angelo Lovece, Alessia Catalano, Maria Maddalena Cavalluzzi, Claudio Bruno, Annalisa De Palma, Marialessandra Contino, Maria Grazia Perrone, Nicola Antonio Colabufo, Alberto Chiarini, Carlo Franchini, Carla Ghelardini, Solomon Habtemariam, Giovanni Lentini

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Key concepts: Mexiletine, Chronotropic, Chemistry, Inotrope, Pharmacology, Antagonist, Antiarrhythmic agent, Biological activity

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