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[Analysis of the result of 409 cases with liver cirrhosis and severe hepatitis by using the model for end-stage liver disease].

Chunhui Song, Liming Chen, Lingxia Zhang

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Abstract

OBJECTIVE: To analyze the influence of the model for end-stage liver disease (MELD) results in 409 cases with liver cirrhosis and severe hepatitis and compare with Child-Pugh scoring system. METHODS: The data of 409 patients with liver cirrhosis and severe hepatitis were collected and analyzed by using the Child-Pugh and MELD scoring systems, and Chiss statistical software was applied. RESULTS: There is a statistical significance between either results of MELD of group A, B, C, D; there is a statistical significance between either group in total serum bilirubin and creatinine, but not in INR. CONCLUSION: The changes in total serum bilirubin and creatinine can influence the result significantly, not the INR, and a better way to predict the prognosis of severe liver disease may be application of MELD combined with clinical experience.

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OBJECTIVE: To analyze the influence of the model for end-stage liver disease (MELD) results in 409 cases with liver cirrhosis and severe hepatitis and compare with Child-Pugh scoring system. METHODS: The data of 409 patients with liver cirrhosis and severe hepatitis were collected and analyzed by using the Child-Pugh and MELD scoring systems, and Chiss statistical software was applied. RESULTS: There is a statistical significance between either results of MELD of group A, B, C, D; there is a statistical significance between either group in total serum bilirubin and creatinine, but not in INR. CONCLUSION: The changes in total serum bilirubin and creatinine can influence the result significantly, not the INR, and a better way to predict the prognosis of severe liver disease may be application of MELD combined with clinical experience.

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Available abstract

OBJECTIVE: To analyze the influence of the model for end-stage liver disease (MELD) results in 409 cases with liver cirrhosis and severe hepatitis and compare with Child-Pugh scoring system. METHODS: The data of 409 patients with liver cirrhosis and severe hepatitis were collected and analyzed by using the Child-Pugh and MELD scoring systems, and Chiss statistical software was applied. RESULTS: There is a statistical significance between either results of MELD of group A, B, C, D; there is a statistical significance between either group in total serum bilirubin and creatinine, but not in INR. CONCLUSION: The changes in total serum bilirubin and creatinine can influence the result significantly, not the INR, and a better way to predict the prognosis of severe liver disease may be application of MELD combined with clinical experience.

Key concepts: Cirrhosis, Medicine, Gastroenterology, Liver disease, Bilirubin, Creatinine, Internal medicine, Model for End-Stage Liver Disease

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[Analysis of the result of 409 cases with liver cirrhosis and severe hepatitis by using the model for end-stage liver disease]. — Research Paper | ScholarLens