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2000•Journal of Taishan Medical CollegeRequires access

Relationship between recurrent spontaneous abortion and Th2 Cytokines

Yu Ai

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Abstract

Objetive: To investigate the changes of serum levels of Th2 Cytokines in patients with recurrent spontaneous abortion. Methods: Serum levels of IL 6, IL 10 were measured by enzyme linked immunosorbant assay (ELISA) in 69 cases of recurrent spontaneous abortion(RSA). RSA were randomly divided into two groups: early RSA and delayed RSA. 20 normal pregnant and 20 nonpregnant women were control groups. Results: The serum level of IL 6 in RSA group was obviously higher than that of normal control groups (P0 01); The level IL 6 in RSA had a negative correlation with the serum level of IL 10 (P0 05).The serum level of IL 10 in RSA was markedly lower than that in control groups (P0 01). Conclusion:Changes of IL 6,IL 10 in pregnant women might cause RSA

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What this paper is about

Objetive: To investigate the changes of serum levels of Th2 Cytokines in patients with recurrent spontaneous abortion. Methods: Serum levels of IL 6, IL 10 were measured by enzyme linked immunosorbant assay (ELISA) in 69 cases of recurrent spontaneous abortion(RSA). RSA were randomly divided into two groups: early RSA and delayed RSA. 20 normal pregnant and 20 nonpregnant women were control groups. Results: The serum level of IL 6 in RSA group was obviously higher than that of normal control groups (P0 01); The level IL 6 in RSA had a negative correlation with the serum level of IL 10 (P0 05).The serum level of IL 10 in RSA was markedly lower than that in control groups (P0 01). Conclusion:Changes of IL 6,IL 10 in pregnant women might cause RSA

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Available abstract

Objetive: To investigate the changes of serum levels of Th2 Cytokines in patients with recurrent spontaneous abortion. Methods: Serum levels of IL 6, IL 10 were measured by enzyme linked immunosorbant assay (ELISA) in 69 cases of recurrent spontaneous abortion(RSA). RSA were randomly divided into two groups: early RSA and delayed RSA. 20 normal pregnant and 20 nonpregnant women were control groups. Results: The serum level of IL 6 in RSA group was obviously higher than that of normal control groups (P0 01); The level IL 6 in RSA had a negative correlation with the serum level of IL 10 (P0 05).The serum level of IL 10 in RSA was markedly lower than that in control groups (P0 01). Conclusion:Changes of IL 6,IL 10 in pregnant women might cause RSA

Key concepts: Abortion, Medicine, Positive correlation, Negative correlation, Immunology, Correlation, Physiology, Internal medicine

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