2014•Liaoning Zhongyiyao Daxue xuebaoRequires access

Studies on Preparation of Baicalin Bilayer Tablets

Li L

Abstract

Objective:To study the preparation method of Baicalin Bilayer Tablets. Method:The content of baicalin bilayer tablets was determined by HPLC method. The wet granulation production of double layer tablets was used. Results:Baicalin was linear in the range of 0.03~0.15 μg(r=0.9997),and the average recovery was 98.4%,RSD was 1.58%. The prepared tablets,a quick release layer within 2 min completed disintegration. Bilayer tablet disintegration time lasted 8 hours and the hardness was moderate. Conclusion:The quality control method for Baicalin Bilayer Tablets quality control is suitable for double-layer tablets and it is a simple preparation process which meets the design requirements.

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Key concepts: Baicalin, Bilayer, Granulation, Medicine, Chromatography, Biomedical engineering, High-performance liquid chromatography, Composite material