Efficacy and safety evaluation of Cefepime for the treatment of elderly patients with lower respiratory tract infection

Objective To evaluate the efficacy and safety and antimicrobial resistance of cefepime for the treatment of elderly patients with lower respiratory tract infection. Methods A total of 65 patients with lower respiratory tract infection were treated with cefepime (1.0-2.0g/day iv q12h) in an open clinical study. Results The total efficacy rate of cefepime was 70.77%. with cure rate of 53.85%. bacteria elimination rates were 71.8%. The hight sensitive rate was 63.6%, The moderate sensitive rate was 75.5%, The resistance rate was 24.5%, adverse events was 29.2% (19/65). Conclusions The study shows that cefepime is well tolerated and effective in treating lower respiratory tract infection of elderly patients .