A study of senile patients with urinary tract infection:The distribution of bacteria and drug tolerance analysis

Objective To guide the use of clinical drugs by studying the spctrum of pathogens isolated from urinary tract infection in senile patients and the drug resistance to antibiotics.Methods All the pathogens isolated from urine in senile patients from my hospital in last five years were studied.Bacterial susceptibility test was carried out by using Kirby-Baner method.Results Two hundred and twenty-four strains including 153 strains(68.3%)of Gram negative bacilli,48 strains(21.4%)of gram positive cocci,23 strains(10.3%)of fungi were collected.E.coli showed the highest detection rate of 36.6%(82)in gram-negative bacteria,followed by Klebsiella pneumonia with 7.6%(17).E.coli.Klebsiella and Staphylococcus were the main microorganisms.9.8% of E.coli and 17.6% of Klebsiela were suspected to produce extended-spoctrum β-lactamase.The effective agents against gram negative organisms were imipenem,while the drug resistance rates of Gram negative bacilli to ciprofloxacin and piperacillin were above 49%.The drug resistance rate of gram positive cocci to SMZCO and erythromycin were above 40%,but the vancomycin resistant strain had not been found.Conclusions The drug resistance of bacteria in senile patients urinary tract infections is increasing.Gram negative bacilli is the main pathogen,and is susceptible to imipenem.Vancomycin is the first choice to treat infection with Gram positive cocci.