Clinical analysis of gram-negative bacteria causing pulmonary infections in senile patients

OBJECTIVE To explore the distribution of gram-negative bacteria causing pulmonary infections in senile patients and put forward nursing measures so as to provide guidance for reasonable clinical treatment.METHODS Totally 402 cases of senile patients with pneumonia caused by the gram-negative bacteria,who were treated in the hospital from Jan 2009 to Jun 2009,were enrolled in the study,then the general clinical data of the subjects were collected,the sputum specimens and the lower respiratory tract secretions were cultured for the identification of the strains,and the drug susceptibility testing was performed with the use of K-B method.RESULTS A total of 402 strains of gram-negative bacteria haven been isolated,among which there were 172(42.8%)strains of Pseudomonas aeruginosa,75(18.6%)strains of Klebsiella pneumoniae,43(10.7%)strains of Acinetobacter baumannii,37(9.2%)strains of Escherichia coli,24(6.0%)strains of Enterobacter cloacae,23(5.7%)strains of Haemophilus influenzae,and 28(7.0%)strains of other species of gram-negative bacteria.The main species of the gram-negative bacteria have produced drug resistance to the commonly used antibiotics;the drug resistance rates of the P.aeruginosaand A.baumannii to carbapenems varied between 10.5% and 16.3%.Of totally 402 patients,379 cases were cured with the cure rate of 94.2%,and 18cases died with the mortality of 4.48%. CONCLUSIONThe drug resistance rates of the gram-negative bacteria causing pulmonary infections in the senile patients are increased year by year,thus the comprehensive prevention and control measure,the clinical treatment combined with clinical nursing,should be taken for the treatment of the disease.