Lower respiratory tract infection of the Enterobacteriaceae bacteria ESBLs detection and analysis of relevant factors

Objective Analysis of the production of ESBLs lower respiratory tract infections common Enterobacteriaceae bacteria resistance and resistance characteristics,as well as ESBLs producing bacteria infection in patients with risk factors for clinical use for reference.Methods In February 2007 to August 2008 the bacteria of the Enterobacteriaceae separation from the lower respiratory tract infection with BIOMERIEUX ATB1525 microbial analyzer to identify,detect ESBLs phenotype and drug sensitivity tests.Results In the detection of Enterobacteriaceae bacteria,ESBLs positive rate was 41.3%,Escherichia coli,Klebsiella pneumoniae and Enterobacter cloacae of the enzyme production rates were 42.0%、52.0% and 35.1%.All ESBLs producing strains were susceptible to carbapenems.The resistance rate of to most antibioticswas much higher than those of non-ESBLs producing strains.Conclusion ESBLs producing bacteria infection risk factors for long-term use of third-generation cephalosporins,the use of immunosuppressive agents,ICU patients,catheterization done intubation,the move had major surgery,chronic wasting disease patients.ESBLs production treatment of infections caused by bacteria,imipenem should be chosen,or β-lactamase inhibitor of the complex,third-generation cephalosporin drugs used with caution.