The treatment of flupentixol and melitracen(deanxit) combined with omeprazole in treating functional dyspepsia

Objective:To investigate the effecacy of Flupentixol and Melitracen(Deanxit) combined with antacids,prokinetics agents combined with antacids and monotherapy with prokinetics agents in treating patients with functional dyspepsia(FD) of non-related with consumption,who were with pain in the upper abdomen,burning sensation,acid eructation and feeling full in advance as the main clinic symptoms.Methods:130 patients with FD were randomly divided into 3 groups:1 treatment group(50 cases),and 2 control groups(group A,40 cases;Group B,40 cases).Patients in group A were treated by Mosapride(prokinetic agents) combined with Omeprazole(proton pump inhibitor,PPI),patients in group B were treated by Mosapride only;while patients in the treatment group were treated by Omeprazole combined with Flupentixol and Melitracen(Deanxit) every day.And the course of treatment for each group was four weeks.Compared with patients in the 2 control groups,the rate of marked improvement and rates of improvement for patients in the treatment group are all better(P0.01).Furthermore,the adverse reaction is light.Conclusions:The application of Flupentixol and Deanxit combined with antacids is quite effective in treating patients with FD.