Comparison of Different Extraction Methods for Active Ingredients for Salvia miltiorrhiza Bge. of Fangling

Objective To optimize the best extraction condition for liposoluble and water-soluble ingredients in Salvia miltiorrhiza Bge.of fangling. Methods The semi-bionic-cellulase zymolysis,alcohol and water dual extraction and integration extraction were compared by regarding the contents of TanshinoneⅡA,salvianolic acid-B,total phenolic acid and extracta sicca in Salvia miltiorrhiza Bge.of fangling as indicators and referring to the reflux extraction(Chinese Pharmacopoeia 2010). Results The semi-bionic-cellulase zymolysis extraction was the most efficient technique. Conclusion Semi-bionic-cellulase zymolysis for extraction of Salvia miltiorrhiza Bge.from fangling is the most scientific and suitable method.