2010•Zhongguo shiyan fangjixue zazhiRequires access

Study on Optimum Integration Technique of Semi-bionic Extraction for Salvia miltiorrhiza by Orthogonal Test

Hao Xin-cai

Abstract

Objective: To optimize the best semi-bionic extraction condition of liposoluble and water-solubility ingredients from Salvia miltiorrhiza Bge.Method: The semi-bionic extraction condition was optimized by making the extraction ratios of tanshinoneⅡA,salvianolic acid B,total phenolic acid and dried extract weight as indices.The experiment was designed by a orthogonal test.Result: Optimum extraction condition was: alcohol 70%,time 2 h,stock ratio 1∶ 18(g·mL-1,mass: volume).Conclusion:The method of semi-bionic extraction-70% ethanol extractions is scientific and rational.

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Key concepts: Salvia miltiorrhiza, Extraction (chemistry), Chromatography, Solubility, Chemistry, Stock solution, Mathematics, Organic chemistry