The correlation of heart function to plasma brain natriuretic peptide and high sensitivity C-reactive protein in patients with pulmonary with heart failure

Objective To discuss the relationship of cardiac function to plasma brain natriuretic peptide(NBP) and high sensitivity C-reactive protein(hs-CRP) in pulmonary with heart failure,so as to provide scientific evidence for diagnosing and evaluating pulmonary with heart failure on clinical.Methods A total of 70 cases of patients with pulmonary with heart failure from Jun 2012 to Oct 2014 in our hospital were selected as study group and classified by their heart function.At the same time,70 cases of health people were selected as control group.All the research subjects' serum BNP and hs-CRP were detected in 24 hours.Results The concentration of plasma BNP and hs-CRP were(431.56±89.74)pg/m L and(71.48±21.05)ng/m L respectively in study group,and higher than those in control group [(36.37±9.53)pg/m L and(6.88±3.05)ng/m L],the differences were significant.With the increase of heart function grading,the concentration of plasma BNP and hs-CRP gradually increased,and differences were significant(P 0.05).Conclusion Both plasma BNP and hs-CRP may reflex the condition severity of heart failure.In clinical application,we could use the concentration of plasma BNP and hs-CRP as important supplements to evaluate cardiac function in patients with heart failure.