Determination of vanillin,ferulic acid and vanillic acid by capillary zone electrophoresis

A method has been established to determine vanillin,ferulic acid and vanillic acid in Chinese medicines by capillary zone electrophoresis.Under the optimized conditions,the three analytes were well separated in 10 min.A good linear relationship existed between peak area and concentration in the 2～200,2～200 and 1～200μg·mL~(-1) concentration range for vanillin,ferulic acid and vinillic acid,respectively.The detection limits,based on three times noise were 0.49,0.56,0.38μg·mL~(-1) for vanillin,ferulic acid and vanillic acid,respectively.The developed method was applied to determine vanillin,ferulic acid and vanillic acid in Chinese medicine with good results.To further verify the viability of the method,recovery experiments were carried out,the results were satisfactory.