Performance Evaluation of BC-5500 Hematology Analyzer

Objective To evaluate the performance of BC -5500 hematology analyzer. Methods The indexes including precision, total reproducibility, carry -over, linearity (dilution effect) and comparability were examined according to published evaluation standard. At the same time, comparison of differential count (DC) produced by the analyzer and manual methods. Results Precision, carry-over and total reproducibility in counting of leucocytes, erythrocytes, platelets and examming of hemoglobin on the analyzer were showed in the prescriptive range. There were also good linearity in normal and pathological range and the results correlated well with those obtained on Sysmex XE-2100 (r0.99). DC: reproducibility was good for neutrophils, lymphocytes monocytes, eosinophils and basophils. Comparison of the results by instrument with manual for normal samples in morphology, the correlation was better for neutrophils, lymphocytes and eosinophils (r:0.968～0.983) ,good for monocytes(r=0.917), not good for basophils(r=0.659);The WBC scattergram would change and alarm flags would display when there are neutrophilic stab granulocytes, abnormal or atypical lymphocytes and immature cells in higher proportion.Conclusions The analyzer can be used to test blood cell parameters accurately and reliably. Its main performance indices accorded with the experimental requirements; The results were credible. It is necessary to check with microscopy for DC before reported when it were doubtted.