Relation of plasma B-type natriuretic peptide levels to the changes in left ventricular diastolic function and Tei index in patients with acute myocardial infarction

Objective : To evaluate the relationship between plasma B-type natriuretic peptide levels and left ventricular diastolic function including Tei index in patients with acute myocardial infarction(AMI).Methods : A total of 210 patients with acute anterior myocardial infarction were included in this study.Plama BNP was measured at a median of(24.6±10.2) hours from symptom onset.Left ventricular diastolic function including Tei index was measured using tissue Doppler imaging within 30 days after AMI.Gender,age,heart rate,blood pressure,fasting plasma glucose,total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),and coronary disease severity were analyzed.Results : Patients were divided into four groups according to their BNP levels.The Tei index was elevated with the increase in plasma BNP levels.Multivariate logistic regression analyses showed that BNP was independently associated with IRT,DT,e/a,E/A,and S/D.Multiple regression analysis showed that Tei index was independently associated with BNP(P0.01).Conclusion : BNP is closely related to left ventricular diastolic function after acute myocardial infarction.BNP and Tei index can be used as short-term clinical prognostic factors in patients with acute myocardial infarction.