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2013•Journal of Logistics University of CAPFRequires access

Experimental study of JuGuoDuoFen on the Anti-radical and antioxidant function

Wang Ya-tin

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Abstract

【Objective】To study the Anti-radical and antioxidant function of compound JuGuoDuoFen in rats.【Methods】40 old rats were randomly divided into 5 groups: 3 compound JuGuoDuoFen groups(25,50,100 mg/kg),VE group,control group.All group rats were treated with drugs or NS through oral gavage.The activities of superoxide dismutase(SOD) and glutathione peroxidase(GSH-Px) in blood,the contents of malodndaldegyde(MDA) in plasma,lipofuscin(LF)in heart were determined by biochemical methods.【Results】 compound JuGuoDuoFen could significantly improve the activities of SOD and GSH-Px in blood(P 0.01),decrease the contents of the MDA and LF(P 0.05).【Conclusions】compound JuGuoDuoFen has obvious anti-aging effects.which may result from its antioxidation enzymes and the prevention of lipid peroxidation in tissues.

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What this paper is about

【Objective】To study the Anti-radical and antioxidant function of compound JuGuoDuoFen in rats.【Methods】40 old rats were randomly divided into 5 groups: 3 compound JuGuoDuoFen groups(25,50,100 mg/kg),VE group,control group.All group rats were treated with drugs or NS through oral gavage.The activities of superoxide dismutase(SOD) and glutathione peroxidase(GSH-Px) in blood,the contents of malodndaldegyde(MDA) in plasma,lipofuscin(LF)in heart were determined by biochemical methods.【Results】 compound JuGuoDuoFen could significantly improve the activities of SOD and GSH-Px in blood(P 0.01),decrease the contents of the MDA and LF(P 0.05).【Conclusions】compound JuGuoDuoFen has obvious anti-aging effects.which may result from its antioxidation enzymes and the prevention of lipid peroxidation in tissues.

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Available abstract

【Objective】To study the Anti-radical and antioxidant function of compound JuGuoDuoFen in rats.【Methods】40 old rats were randomly divided into 5 groups: 3 compound JuGuoDuoFen groups(25,50,100 mg/kg),VE group,control group.All group rats were treated with drugs or NS through oral gavage.The activities of superoxide dismutase(SOD) and glutathione peroxidase(GSH-Px) in blood,the contents of malodndaldegyde(MDA) in plasma,lipofuscin(LF)in heart were determined by biochemical methods.【Results】 compound JuGuoDuoFen could significantly improve the activities of SOD and GSH-Px in blood(P 0.01),decrease the contents of the MDA and LF(P 0.05).【Conclusions】compound JuGuoDuoFen has obvious anti-aging effects.which may result from its antioxidation enzymes and the prevention of lipid peroxidation in tissues.

Key concepts: Lipofuscin, Superoxide dismutase, Antioxidant, Glutathione peroxidase, Lipid peroxidation, Chemistry, Dismutase, Enzyme

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