Utilization of Anti-infectives in Our Hospital from July,2003 to June,2006

OBJECTIVE: To analyze the utilization of various anti-infectives in our hospital and to provide bases for the rational use of antibiotics in the clinic and scientific making of drug purchase plan.METHODS: The analysis was conducted using the method of defined daily use and sequence of consumption sum based on the raw data retrieved from Hospital Drug Inventory Management System.RESULTS: There was a slight increase in the kinds of anti-infectives used during 2003～2005,with cephalosporins showing the most in kinds.Of the total consumption sum of western drugs,the average annual consumption sum of anti-infectives accounted for 32.36%,lower than that in the other domestic hospitals.Beta lactams antibiotics ranked far ahead of others,accounting for 50.99% of the consumption sum of total anti-infectives.Penicilins,cephalosporins,quinolones,macrolides and nitroimidazole were the most commonly used 5 kinds,with average DDDs sum of the five kinds accounted for 85.29% of DDDs sum of total anti-infective drugs in each year.Of the top 20 drugs on the list of DDDs,the ratio of oral preparation to injections was 2∶1,75% were 1 and 25% were 1 in order ratio,suggesting those anti-infectives that with low cost,safety and efficacy assumed a predominant place,and the clinical medication was rational on the whole.CONCLUSION: The information of the use of anti-infectives is of great significance for the rational drug use.