Observation of myocardial ultrasonic intergrated backscatter in patients with type 2 diabetes mellitus

Objetive To study the characteristics and value of myocardial ultrasonic intergrated backscatter (IBS) in patients with type 2 diabetes mellitus. Methods Myocardial IBS were obtained from the left ventricular walls (anterior septum, anterior wall, lateral wall, posterior wall, inferior wall and posterior septum) with HP 5500 ultrasonic instrument in 50 patients with type 2 diabetes mellitus and 50 controls. The difference between diastasis and end systole is CVIB. The values of IBS and CVIB were normalized by the values of simultaneous pericardial IBS and CVIB (IB% and CVIB%). The left ventricular isovolumetric relaxation time (IVRT) and the ratio of peak E and A wave velocities of mitral valve rheography (E/A) were also determined. Results Compared with normal controls, IB% in the left ventricular walls were increased and CVIB were decreased with a significant differences ( P 0.001). IVRT and E/A were in normal ranges in two groups. Conclusion There were significant changes in left ventricular wall IBS and the changes were diffuse and preceded the abnormalities of left ventricular diastolic function (subclinical manifestation of diabetic myocardiopathy). IBS can very early find the presence of diabetic myocardial microstructural lesion