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2003•Journal of Henan University of Science & TechnologyRequires access

Diagnosis Value of Determination of Serum CA125 and CEA in Patients with Ovarian Tumors

YU Yan-ni

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Abstract

Objective To study the diagnosis value of combined measurement of the cancer antigen 125 (CA125) and CEA in patients with ovarian tumors.Methods ELISA was used to measure the levels of serum CA125 and CEA in patients with benign ovarian tumor, malignant ovarian tumor and endometriosis. ResultsSerum CA125 level was significantly higher in patients with malignant ovarian tumor than that in those with benign or borderline ovarian tumor or endometriosis and in control group(P0.01). Serum CA125 level was higher in patients with endometriosis and pelvic infection than that in those with benign ovarian tumor and in control group(P0.05). Conclusion The single detection of CA125 may be the best method of diagnosing ovarian epithelioma, and has greater value in diagnosing endometriosis. The combind detection of CA125 and CEA doesn't have significant value in diagnosing malignant ovarian tumor.

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Objective To study the diagnosis value of combined measurement of the cancer antigen 125 (CA125) and CEA in patients with ovarian tumors.Methods ELISA was used to measure the levels of serum CA125 and CEA in patients with benign ovarian tumor, malignant ovarian tumor and endometriosis. ResultsSerum CA125 level was significantly higher in patients with malignant ovarian tumor than that in those with benign or borderline ovarian tumor or endometriosis and in control group(P0.01). Serum CA125 level was higher in patients with endometriosis and pelvic infection than that in those with benign ovarian tumor and in control group(P0.05). Conclusion The single detection of CA125 may be the best method of diagnosing ovarian epithelioma, and has greater value in diagnosing endometriosis. The combind detection of CA125 and CEA doesn't have significant value in diagnosing malignant ovarian tumor.

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Available abstract

Objective To study the diagnosis value of combined measurement of the cancer antigen 125 (CA125) and CEA in patients with ovarian tumors.Methods ELISA was used to measure the levels of serum CA125 and CEA in patients with benign ovarian tumor, malignant ovarian tumor and endometriosis. ResultsSerum CA125 level was significantly higher in patients with malignant ovarian tumor than that in those with benign or borderline ovarian tumor or endometriosis and in control group(P0.01). Serum CA125 level was higher in patients with endometriosis and pelvic infection than that in those with benign ovarian tumor and in control group(P0.05). Conclusion The single detection of CA125 may be the best method of diagnosing ovarian epithelioma, and has greater value in diagnosing endometriosis. The combind detection of CA125 and CEA doesn't have significant value in diagnosing malignant ovarian tumor.

Key concepts: Medicine, Endometriosis, Ovarian cancer, Ovarian tumor, Cancer antigen, Internal medicine, Oncology, Cancer

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