Diagnostic value of determination of serum CA125,CA199 and CEA in patients with ovarian cancer

Objective:To study the diagnostic value of the carbohydrate antigen 125(CA125),carbohydrate antigen 199(CA199) and CEA in patients with ovarian tumors.Methods: Electrochemiluminescence immunoassay was used to measure the levels of serum CA125,CA199 and CEA in 50 patients with benign ovarian tumors,50 patients with mailgnant ovarian tumors and 50 healthy controls.Results: Serum levels of CA125,CA199 and CEA were significantly higher in the patients with malignant ovarian tumor than those with benign ovarian tumors and health controls(P0.001),CA125 levels difference had statistical significance between benign ovarian tumor group and healthy control group(P0.01),while the serum levels difference of CA199 and CEA had no statistical significance(P0.05).Conclusion: The joint detection of CA125,CA199 and CEA may be the best method for diagnosing ovarian tumors,and of great significance in early diagnosis of ovarian cancer,treatment effect monitoring and prognosis judgment.