2009•Journal of clinical and experimental medicineRequires access
The application of noninvasive bilevel continuous airway pressure ventilation on chronic obstructive pulmonary desease complicated by type II respiratory failure and its clinical analysis
Yaguang Li
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Abstract
Objective To observe the application of noninvasive bilevel continuous airway pressure(BiPAP) ventilation on chronic obstructive pulmonary disease(COPD) complicated by type Ⅱ respiratory failure and its clinical analysis.Methods From October 2004 to December 2008,46 cases with COPD complicated by type Ⅱ respiratory failure were randomly classified into two groups with 23 cases in each group.Patients in control group were treated with routine therapy,while patients in treatment group were treated with BiPAP in addition to routine therapy.Treatment effects were compared between the two groups.Results Compared with pretreatment,PaO2 and PaCO2 in control group were significantly improved 3 h after treatment(P0.05),while there were no significant differences in respiration,heart rate and pH(P0.05).Compared with pretreatment,respiration,heart rate and PaCO2 were significantly decreased and PaO2 and pH were significantly increased in treatment group 3h after treatment(P0.05).Moreover,respiration,heart rate,PaO2,PaCO2 and pH in treatment group were significantly improved than those in control group 3h after treatment(P0.05).Compared with control group,the effective rate was higher(P0.05) and the hospitalized time was shorter(P0.05) in treatment group,however,there was no significant difference in case-fatality rate between the two groups(P0.05).Conclusion BiPAP ventilation is noninvasive and cheap.It is also an effective and safe method for the treatment of COPD complicated by type Ⅱ respiratory failure.