Noninvasive positive pressure ventilation for type II respiratory failure in chronic obstructive pulmonary disease

Objective To explore the efficacy of non-invasive positive pressure ventilation for COPD complicated with type Ⅱ respiratory failure.Methods 96 patients with COPD complicated with type Ⅱ respiratory failure were assigned to BiPAP plus conventional therapy(treatment group) or conventional therapy alone(control group).42 patients were divided into control group treated with conventional therapy,including oxygen therapy,airway control,antibiotics,correcting acid-base imbalance and respiratory stimulant.54 patients were divided into treatment group treated with noninvasive BiPAP with oral-nasal mask in addition to conventional therapy.Noninvasive BiPAP were lasted 7-14 days in treatment group.The PH,PaCO2,PaO2,respiratory rate(RR),heart rate(HR) and consciousness before and after pressure ventilation were observed.Results The PH,PaCO2 and PaO2 were significantly improved after non-invasive positive pressure ventilation(P0.05).There were significantly difference in ventilatory parameters and average stay between treatment group and control group(P0.05).Conclusion Non-invasive positive pressure ventilation for COPD complicated with type Ⅱ respiratory failure is effective.