Comparative analyses on perioperative utilization of antibiotics in 220 patients undergoing cesarean section

Objective To investigate antibiotic utilization during perioperative period in cesarean section cases, and to provide basis for rational medication in clinic. Methods Retrospective study was done on 220 cases of cesarean section discharged from our hospital during March to May in 2009 and January to March in 2012 to discuss the rationality of perioperative antibiotic utilization. Results The ratio of peroperative use of antibiotics for patients undergoing cesarean section, before and after control of antibacterials, were 95.5% and 94.4 % respectively, with the average durations of prophylaxis at 4.7 and 3.8 days and the longest durations at 7 and 6 days. Conclusion After control of antibacterials, the rate of antibacterial utilization for cesarean section patients has decreased by 1.1 %, the average duration of medication has shortened by 0.9 day, the rate of two-drug and three-drug utilization has decline in 22.9% and 2.6% respectively. The longest duration of perioperative antibiotic prophylaxis has shortened by 1 day. However, there still exist some problems, such as inappropriate choice of drugs, irrational combination therapy, long course of treatment, improper medication timing, nonstandard usage and dosage, low rate of specimens tested etc. It is necessary to strengthen supervision in order to promote rationality of perioperative antibiotic utilization.