Investigation of perioperative antibiotics application in clinical parturients undergoing cesarean section

Objective:To investigate the preventive use of antibiotics during perioperative period in cesarean section cases in our hospital,and explore the reasonable application of antibiotics.Methods:Retrospective analysis of the perioperative using of antibiotics of 200 cases cesarean section during January 2008-January 2010.The cases were divided into two groups.Antibiotics used no more than 48 h and the other group was over 72 h.Infection rate,postoperative antifebrile time,hospitalization days,hospitalization fee and adverse reaction of the two groups were compared.Results:Antibiotics used no more than 48 h was 28 percent,while over 72 h was 72 percent.There was no significant difference on infection rate,wound infection rate,postoperative antifebrile time and hospitalization days of the patients between the two groups(P0.05).Nevertheless,hospitalization fee and adverse reaction of patients in no more than 48 h group were notably low than over 72 h group(P0.01).Conclusion:Our antibacterial prophylaxis application time in cesarean section puerpera perioperation is long.the preventive use of antibiotics no more than 48 h is meaningless in postoperatie complications and instead it increases economic burden of the patients.The perioperative antibacterial application should be pressed with intervention principles.