2000•Zhonghua neifenmi daixie zazhiRequires access

Effect of angiotensin II receptor antagonist on the plasma levels of calcitonin gene-related peptide and endothelin in the patients with diabetic nephrophy

Cui-ping Cao, Guoliang Liu, Binhong Wen

Abstract

The plasma levels of calcitonin gene-related peptide (CGRP) and endothelin (ET) were assayed in 76 patients with diabetic nephropathy (DN) and 23 healthy subjects, and the changes of CGRP and ET levels after treatment with angiotensin Ⅱ receptor antagonist (ARBS) were observed. The results showed that CGRP level was increased and ET level decreased after treatment with ARBS, which seemed to delay the onset and development of DN.

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Key concepts: Calcitonin gene-related peptide, Endocrinology, Internal medicine, Endothelin receptor, Calcitonin, Antagonist, Diabetic nephropathy, Medicine