2009•Practical Preventive MedicineRequires access

Clinical Significance of Detection of Serum Cystatin C in Early Stage of Diabetic Nephropathy

Rong He

Abstract

Objective To investigate the clinical significance of serum cystatin C(Cys C) level in the early stage of diabetic nephropathy. Methods Serum Cys C levels of 100 patients with early stage of diabetic nephropathy were detected by particle enhanced immunonephelometric assay,serum urea(Sur)and serum creatinine(Scr) were measured by biochemistry analysis.100 health check-up individuals were selected as control group. Results The levels of Cys C,Sur and Scr in diabetic nephropathy group were significantly higher than those of the control group(P0.01;P0.05;P0.05).The level of Cys C was correlated positively with Sur and Scr(both P0.01).The positive detection rate of serum Cys C in diabetic nephropathy group was 66.0%,which was significantly higher than that of serum Sur(20.0%;P0.05) and Scr(14.0%;P0.01).Conclusions The positive detection rate of serum Cys C is higher in diabetic nephropathy group.It is considered that Cys C is a good serological indicator for evaluating early stage damage in kidney of diabetic nephropathy.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Diabetic nephropathy, Cystatin C, Creatinine, Nephropathy, Medicine, Internal medicine, Clinical significance, Renal function