Pharmacoeconomical analysis of gatifloxacin and levofloxacin in treatment of urinary tract infection

Objective To analyze the cost-effect of gatifloxacin and levofloxacin in treatment of urinary tract infection.Methods 80 cases with urinary infection were randomly divided into 2 groups,in which they were treated with gatifloxacin and levofloxacin,respectively.The cost-effect in two groups was analyzed and compared with each other by pharmacoeconomical method.Results There was no significant difference in therapeutic effect between two groups(P0.05),such as effective rate of 92.5% and95.0%,bacterial clearance rates of 92.6% and 85.7% and undesired event rates of 3.61% and 4.22% in gatifloxacin group and levofloxacin group.However,there was significant difference in cost-effect ratio between two group,83.0 and 45.5 respectively in gatifloxacin group and levofloxacin group(P0.05).Conclusion Levofloxacin has cost-effect advantage over gatifloxacin in the treatment of urinary tract infection.