Wenxinkeli combined with amiodarone for ventricular arrhythmia in senile patients with coronary heart disease

Objective To evaluate the therapeutic efficacy and safety of wenxinkeli combined with amiodarone for ventricular arrhythmia in senile patients with coronary heart disease. Methods Eighty-nine patients with ventricular arrhythmia were divided into three groups. In group A the cases treated by the use of wenxinkeli with amiodarone, but only with the aid of amiodarone or wenxinkeli for cases in group B or C. Then the improvement of clinical symptoms, ventricular arrhythmia and the incidence of side effect were observed. Results After treatment the total effective rate was 91.18% in group A, 68.96% in group B, and 69.23% in group C. There was a significant statistical difference between group A and group B or group A and group C(P0.05), but without difference between group B and group C(P0.05). The improvement of clinical symptom in group A was markedly better than that in group B and C(P0.05), and the incidence of the side effect ingroup A and C was lower than that in group B. Conclusion Wenxinkeli combined with amiodarone is more effective and safe for ventricular arrhythmia in senile patients than that the single amiodarone or wenxinkeli.