Curative Effect Analysis of Wenxinkeli in Treatment of Cardiac Arrhythmia

Objective To study the anti-arrhythmia effect and safety of Wenxinkeli for the patients with cardiac arrhythmia.Methods 150 patients with cardiac arrhythmia were divided into therapy group and control group at random,75 in every group.Therapy group took Wenxinkeli 9 g,3 times a day,and control group took Propafenone 100 mg,3 times a day,4 weeks for one period of treatment.The curative effect's was assessed by the clinical symptoms and the change of 24 hours dynamic electrocardiogram.Results The clinical total effective rate of therapy group was higher than that of control group(82.67% vs 64.00%,χ2=6.682,P=0.010),and The ECG total effective rate of therapy group was higher than that of control group(76.00% vs 58.67%,χ2=5.122,P=0.024).But there was no significant difference between two groups in the ECG total effective rate on artrial fibrillation (56.52% vs 61.90%,χ2=0.132,P=0.717).Conclusion As other drug for cardiac arrhythmia,Wenxinkeli could improve the therapeutic effect in the treatment of atrial or ventricular premature beat,which should be safe and better than Propafenone.But the therapeutic effect of Wenxinkeli on atrial fibrillation was not superior to Propafenone.