Therapeutic Effect of Collagenase and Oxygen-Ozone in Patients with Lumbar Disc Herniation

Objective To evaluate the clinical effect of chemonucleolysis with collagenase and oxygen-ozone in lumbar disc herniation.Methods 90 cases with lumbar disc herniation confirmed by clinic,CT or MRI were randomly divided into the control group (collagease was injected outside the lumbar disc) and treatment group (based on the treatment of control group,oxygen-ozone was injected into lumbar disc).Results 90 cases were followed-up after the operation for 3 months. The excellent rate was 37.8% in the control group, 68.9% in the treatment group. The excellent or good rate was 93.3% in the control group, 95.6% in the treatment group. The excellent rate was significantly higher in the treatment group than that in the control group (P0.05).Conclusion The therapeutic effect using collagenase combined with ozone to treat lumbar disc herniation is satisfactory.