2007Di-Si Junyi Daxue xuebaoRequires access

Analysis on antimicrobial resistance of gram-negative bacilli in intensive care unit

Xiao Li

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Abstract

AIM: To investigate the distribution and drug resis- tance of gram-negative bacilli in our intensive care unite (ICU). METHODS: Antimicrobial susceptibility testing of clinically isolated gram-negative bacilli were performed by using Kirby-Bauer methods and the results were analyzed according to National Committee for Clinical Laboratory Standards (NCCLS, 2003). RESULTS: Acinetobacter spp (25.0%), E. coli (18.5%), klebsiella spp (16.7%), P. aeruginosa (13.8%) and S. maltophilia (11.2%) were most frequently isolated. ESBLs-pro- ducing strains were detected in 41.1% of E.coli and 51.1% of Klebsiella spp strains. Nonfermenting gram-negative bacilli were very highly resistant to most antimicrobial agents. CONCLUSION: It is important to monitor the antimicrobial resistance of clinical pathogens and rationally use the antibiotics.

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What this paper is about

AIM: To investigate the distribution and drug resis- tance of gram-negative bacilli in our intensive care unite (ICU). METHODS: Antimicrobial susceptibility testing of clinically isolated gram-negative bacilli were performed by using Kirby-Bauer methods and the results were analyzed according to National Committee for Clinical Laboratory Standards (NCCLS, 2003). RESULTS: Acinetobacter spp (25.0%), E. coli (18.5%), klebsiella spp (16.7%), P. aeruginosa (13.8%) and S. maltophilia (11.2%) were most frequently isolated. ESBLs-pro- ducing strains were detected in 41.1% of E.coli and 51.1% of Klebsiella spp strains. Nonfermenting gram-negative bacilli were very highly resistant to most antimicrobial agents. CONCLUSION: It is important to monitor the antimicrobial resistance of clinical pathogens and rationally use the antibiotics.

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Available abstract

AIM: To investigate the distribution and drug resis- tance of gram-negative bacilli in our intensive care unite (ICU). METHODS: Antimicrobial susceptibility testing of clinically isolated gram-negative bacilli were performed by using Kirby-Bauer methods and the results were analyzed according to National Committee for Clinical Laboratory Standards (NCCLS, 2003). RESULTS: Acinetobacter spp (25.0%), E. coli (18.5%), klebsiella spp (16.7%), P. aeruginosa (13.8%) and S. maltophilia (11.2%) were most frequently isolated. ESBLs-pro- ducing strains were detected in 41.1% of E.coli and 51.1% of Klebsiella spp strains. Nonfermenting gram-negative bacilli were very highly resistant to most antimicrobial agents. CONCLUSION: It is important to monitor the antimicrobial resistance of clinical pathogens and rationally use the antibiotics.

Key concepts: Bacilli, Microbiology, Antimicrobial, Acinetobacter, Pseudomonas aeruginosa, Antibiotic resistance, Drug resistance, Antibiotics

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