Evaluation of early parenteral nutrition and enteral nutrition in totalgastrectomy

Objective To evaluate the efficacy of early parenteral nutrition and enteral nutrition in the patients of total gastrectomy.Methods Forty-eight patients with total gastrectomy for gastric cancer surgery were randomly divided into groups of early parenteral nutrition and enteral nutrition group,24 patients in each group.Immune function index,complication rate and postoperative intestinal function recovery time and average hospital stay were observed.Results EN group and TPN group had early recovery time of postoperative anal exhaust,low complication rate,and short postoperative hospitalization time compared with the control group.There was significant difference between the two groups(P0.05).The total protein,albumin,transferrin level in EN group was significantly higher than that in the TPN group in postoperative day 3 and postoperative day 14(P0.05).CD4+ T cells,NK cells,IgM,and IgGwere significantly increased in two groups on seventh day.A statistical significant difference was found between EN and TPN group(P0.05).Conclusion Early EN total after gastrectomy are safe and effective nutritional support ways,which can quickly restored patients' immune status,shorten the intestinal function recovery time and the length of time.