2012Clinical Journal of Medical OfficersRequires access

Clinical comparison of early postoperative enteral nutrition and parenteral nutrition after gastric cancer operation

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Abstract

Objective To evaluate the efficacy of early enteral nutrition(EN) and total parenteral nutrition(TPN) after total gastrectomy. Methods Forty-eight patients of total gastrectomy for gastric cancer surgery were randomly divided into EN and TPN groups,24 patients in each group.Clinical symptoms,complication,average hospital stay,changes in serum protein before and after operation and immune function index were observed. Results Postoperative recovery time of anal exhaust was earlier,complication rate was lower and postoperative hospitalization time was shorter in EN group than in TPN group(P0.05).3d and 14d after operation,the total protein,albumin,transferrin levels were higher in EN group than in TPN group.7d after operation,CD4+T cells,NK cells,IgM and IgG increased in both groups.There was statistical significant difference between two groups(P0.05). Conclusion Early EN after total gastrectomy is an safe and effective nutritional support way,which can quickly restore patients'immune status,shorten the intestinal function recovery time and the hospitalization time.

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Objective To evaluate the efficacy of early enteral nutrition(EN) and total parenteral nutrition(TPN) after total gastrectomy. Methods Forty-eight patients of total gastrectomy for gastric cancer surgery were randomly divided into EN and TPN groups,24 patients in each group.Clinical symptoms,complication,average hospital stay,changes in serum protein before and after operation and immune function index were observed. Results Postoperative recovery time of anal exhaust was earlier,complication rate was lower and postoperative hospitalization time was shorter in EN group than in TPN group(P0.05).3d and 14d after operation,the total protein,albumin,transferrin levels were higher in EN group than in TPN group.7d after operation,CD4+T cells,NK cells,IgM and IgG increased in both groups.There was statistical significant difference between two groups(P0.05). Conclusion Early EN after total gastrectomy is an safe and effective nutritional support way,which can quickly restore patients'immune status,shorten the intestinal function recovery time and the hospitalization time.

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Available abstract

Objective To evaluate the efficacy of early enteral nutrition(EN) and total parenteral nutrition(TPN) after total gastrectomy. Methods Forty-eight patients of total gastrectomy for gastric cancer surgery were randomly divided into EN and TPN groups,24 patients in each group.Clinical symptoms,complication,average hospital stay,changes in serum protein before and after operation and immune function index were observed. Results Postoperative recovery time of anal exhaust was earlier,complication rate was lower and postoperative hospitalization time was shorter in EN group than in TPN group(P0.05).3d and 14d after operation,the total protein,albumin,transferrin levels were higher in EN group than in TPN group.7d after operation,CD4+T cells,NK cells,IgM and IgG increased in both groups.There was statistical significant difference between two groups(P0.05). Conclusion Early EN after total gastrectomy is an safe and effective nutritional support way,which can quickly restore patients'immune status,shorten the intestinal function recovery time and the hospitalization time.

Key concepts: Medicine, Parenteral nutrition, Gastrectomy, Complication, Gastroenterology, Enteral administration, Surgery, Immune system

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