Therapeutic Effect Observation on Chronic Hepatitis B Treated with Compound Glycyrrhizin Plus Urˉsodeoxycholic Acid

OBJECTIVE:To observe the therapeutic effect of compound glycyrrhizin combining ursodeoxycholic acid in the treatment of chronic hepatitis B.METHODS:87patients with chronic hepatitis B were enrolled to,on whom,the anti-viral therapy proved to be ineffective and who suffered a long-term abnormal liver functions,of the total,47were randomly asˉsigned to receive compound glycyrrhizin plus ursodeoxycholic acid(treatment group),and40to receive compound glycyrrhizin plus vitamin C(control group).Course of treatment for both groups was8weeks.RESULTS:As compared with the control group,the liver function and immune function for the treatment group had a better amelioration(P0.05);the total effective rates of the treatment group and the control group were89.4%and67.5%(P0.01),respectively.CONCLUSION:Comˉpound glycyrrhizin plus ursodeoxycholic acid is effective in the treatment of chronic hepatitis B cases when anti-viral therapy is ineffective and whose liver functions are abnormal for a long time.