Observing the Effect of Glycyrrhizinate Comownd Ursodeoxycholi acid on Treating Chronic Hepatits B

Objective: To observe the therapeutic effect of compound glycyrrhizin combining ursodeoxy-cholic acid in the treatment of chronic hepatitis B.Method: 87 patients with chronic hepatitis B were enrolled to,on whom,the anti-viral therapy proved to be ineffective and who suffered a long-term abnormal liver functions,of the total,47 were randomly assignesd to receive compound glycyrrhizin plus ursodeoxycholic acid(treatment,group),and 40 to receive compound glycyrrhizin plus vitamin C(control group).Course of treatment for both groups was 8 weeks.Result: As compared with the control group,the liver function and immune function for the treatment group had a better amelioration(P0.05));the total effective group,the liver function and immune control group were 89.4% and 67.5%(P0.01),respectively.Conclusion: Compound glycyrrhizin plus ursodeoxycholi acid is effective in treatment of chronic hepatitis B cases when anti-viral therapy is ineffective and whose liver function are abnormal for a long time.