Influence of Uu and AsAb on semen quality

Objective To study the influence of Uu and serum antisperm antibodies(AsAb) on the main parameters of semen.Methods 62 cases of male infertility were selected and their secretions were cultured for identification by selective culture medium with Uu.The seminal plasma and serum AsAb,IgM,IgG and IgA were detected by ELISA.The sperm density,sperm survival rate,sperm a+ b activity and sperm deformity rate were detected by the semen analyzer.According to the detected results,the patients were divided into the Uu positive infertile group and Uu negative infertile group and the comparison among the semen items in the two groups were made.Results The sperm deformity rate in the Uu positive infertile group was 25.62%±17.90% and significantly higher than(12.81±8.46)% in the Un negative infertile group(P0.05),and the sperm density,survival ratio and motility in the two groups had no statistical difference(P0.05).The sperm density,survival ratio and motility in the AsAb positive infertile group were(37.21±42.95)×106/mL,(23.82±20.30)% and(11.79±12.62)%,which in the AsAb negative were(90.01±83.52)×106/mL,(52.25±30.10)% and(35.28±23.46)%,showing statistical difference between the two groups(P0.05).But the sperm malformation rate between the two groups had no significant difference(P0.05).The sperm survival ratio and the motility among various AsAb subtypes had statistic difference(P0.05),and the sperm malformation rate and sperm density among various AsAb subtypes showed no statistical difference(P0.05).Conclusion Uu and AsAb seriously affect the semen quality,which have important significance on differential diagnosis and treatment options in male sterile types.