An investigation of the correlation of anti-sperm antibodies and semen parameters

Objective To investigate the influence of anti-sperm antibodies(AsAb) on sperm parameters.Methods The subjects consisted of 51 AsAb positive patients,40 diseased control and 47 healthy control cases.The semen parameters were detected by computer-assisted sperm analyzer,and SPSS 15.0 was used for statistical analysis.Results The sperm motility(%),a+b-level activity(%),and malformation rate(%)were 62.62±10.49,31.81±9.00,and 63.04±7.55 respectively in the AsAb positive group;these were 66.44±8.25,31.40±9.08,and 65.77±8.76 respectively in the diseased control group and 68.73±4.76,35.99±6.44,and 60.85±5.96 respectively in the healthy control group.There were significant differences between 3 groups as to the above mentioned parameters(F values were 6.490,4.979,and 4.140 respectively,P0.05).The AsAb mainly adhered to the tails of sperms.Conclusion AsAb positive may be one of the reasons for decreased sperm motility and vitality of a+b level.