Serotype Distribution and Drug Resistance of 261 Shigella Strains

[Objective]To understand the serotype distribution and drug resistance of Shigella in Minhang District of Shanghai City,and provide scientific evidence for diarrhea prevention and control.[Methods]The serotype of shigella isolated from fecal samples of intestinal diarrhea patients were grouped in Minhang District during 2007-2009.Antibiotic susceptibility was conducted by K-B method.[Results]A total of 261 strains were isolated,shigella flexneri accounted for 72.80%,followed by shigella sonnei which accounted for 27.20%.Ten serotypes(F1a14 strains,F2a100 strains,F2b13strains,F4a4strains,F4c38 strains,FX mutation 7strains,FY mutation11strains,F4b 1strain,F5a1strain,F6 1strain) were distributed in 190 strains of shigella flexneri.The rate of resistance to cotrimoxazole,ampicillin trihydrate,tetracycline,rifampcin,nalidixic acid was 87.36%,88.12%、86.97%,81.23%,96.93% respectively.[Conclusion]Shigella showes seriously multi-drug resistance in Minhang District and should be pay more attention to surveillance and control of drug resistance.