Clinical effects of ketorolac tromethamine on prevention of pain and agitation during anesthesia recovery period after remifentanil anesthesia

Objective: To observe the clinical effects of ketorolac tromethamine for prevention of pain and agitation during anesthesia recovery period after remifentanil anesthesia.Method: A total of 100 cases scheduled for laparoscopic cholecystectomy aged between 40-60 years,categoried as ASA Ⅰ-Ⅱ stage,were randomly divided into two groups with 50 cases in each.30 mg of ketorolac tromethamine was infused intravenously for experimental group 30 min before the end of the operation;1 mL of 0.9% sodium chloride was given for the control group at the same time point.Spontaneous breathing recovery time,recovery time and extubation time were recorded.Pain score and agitation severity score were evaluated 15 and 30 min after extubation.Results: No significant differences were found in spontaneous respiratory recovery time,recovery time,extubation time between the two groups(P0.05);the pain score and agitation severity score of the experimental group were both significantly higher than that in the control group(P 0.01).Conclusions: Ketorolac tromethamine can prevent pain and agitation during anesthesia recovery period after remifentanil anesthesia.