Effect of Atorvastatin on C-reactive Protein in Patients with Unstable Angina in Early Stage

Objective To study the influence of atorvastatin for 3 days on hs-CRP and lipiemic levels for patients with unstable angina.Methods 94 patients with unstable angina in Ankang Central Hospital were random-ized into two groups from May of 2003 to May of 2004:control group and atorvastatin group(20mg/d)for 3 days,then check and compare the changes of hs-CRP and lipiemic levels of the two groups.Result After 3 days administration of atorvastatin,the level of hs-CRP was reduced(P0.01),but no distinct differences between lipiemic levels of the 2 groups occured.Conclusion Atorvastatin for 3 days for patients with unstable angina could reduce the hs-CRP levels and decrease the inflammation of the patients with cornary disease.It promotes the stablization of the atheroselerotic plague,without depending on the change of lipiemic levels.