Distribution of Pathogenic Bacteria in Urinary System Infection and Their Drug Resistance

OBJECTIVE To analyze the pathogenic bacteria′s distribution and their drug resistance in urinary system(infection),and to provide the information for choosing suitable antibiotic.METHODS Totally 294 strains of(pathogenic) bacteria derived from the clinical urinary system infection were analyzed according to the requirements described in the National Regulations on Clinical Laboratory Operations.The bacteria were identified by the(automated) analyzer VITEK-60 made by Bio-Merieux Company in France and the drug resistance was analyzed with the K-B test.RESULTS In the 294 strains of bacteria,75.9% were Gram-negative and 24.1% were(Gram-positive).Most of Gram-negative bacteria were Escherichia and most of Gram-positive bacteria were Enterococcus.Sixty three strains produced extended-spectrum beta-lactamases(ESBLs).90.5%(57 stains) of them were(Escherichia) and(9.5%) percent(6 strains) were Klebsiella pneumoniae.Twenty one strains in Enterococcus resisted to high(concentration) gentamicin and they accounted for 43.7% of Enterococcus.CONCLUSIONS The pathogenic(bacteria) in urinary system infection distribute extensively and some of them are multiple drug resistant,so we suggest that the clinicians pay more attentions to the bacteriology culture and choose the suitable antibiotic(according) to the(results) of antibiotic susceptibility tests,in order to reduce the strains producing ESBLs.