Pathogenic bacteria disrtibution and drug resistance of urinary system infection

Objective To understand patpogen distribution and drug resistance of urinary system infection,and to provide the information for choosing suitable antibiotic.Methods Totally 389 strains of pathogenic becteria derived from the clinical urinary system infection were analyzed according to the requirements described in the National Regulations on Clinicail Laboratory Operations.The bacteria were identified by the automated analyzer API made by Bio-Merieux Company in France and the drug resistance was analyzed with the K-B test.Results In the 389 strains of bacteria,68.9% were Gram-negative and 25.2% were Gram-positive.The first 5 were Escherichia coli(51.4%),cogulasenegative Staphylococcus(CNS,10.8%),Enterococcus(9.5%),Klebsillla pneumoniae(4.9%),Pseudomonas aeruginosa(3.6%).68S trains produced extended-spectrum beta-lactamases(ESBLs).31.5%(63stains) of them were Escherichia and 26.3% percent(5Strains) were Klebsiella pneumoniae.Conclusion G bacilli are the main infectious pathogens inurinary tract infection and antibiotic resistance rates continue to evolve,the clinic should reasonabiy choose the antibiotics according to the test results of the pathogens sensitivity to drugs.