Distribution of pathogenic bacteria in midstream urinary infection and their drug resistance

Objective To analyze the pathogenic bacteria distribution and their drug resistance in urinary system infection, and to provide the information for choosing suitable antibiotic. Methods totally 496 strains of pathogenic bacteria derived from the clinical urinary system infection were analyzed according to the require ments described in the National Regulations on Clinical Laboratory Operations. The bacteria were identified by the automated analyze HEIMA DL ─ 96. Results In the 465 strains of bacteria 77.8% were Gram-negtive 、14.7% were Gram-positive and 7.5% were yest. Most of Gram-negtive bacteria were E.col and most of Gram-negtive bacteria were 128 strains produced extended spectrum beta- lactamases(ESBLs). 40.5%(120 bacteria) of them were E.col and 22.8% percent(8 bacteria) were K.pen. 12 strains were MRS and they accounted for 42.8%, 11 strains in Enterococcus resisted to high concentration gentamicin and they accounted for 36.7% of Enterococcus. Conclusions The pathogenic bacteria in urinary system infection distribute extensively and so me of them are multiple drug resistance, so we suggest that the clinicians pay more attentions to the bacteriology culture and choose the suitable antibiotic according to the Results of antibiotic susceptibility tests.